10.2: Inheritance
Teaching time allocated: 3 hours
Practical time allocated: 0 hours
key vocab
prior learning & retrieval practice
Review topic 3.4 inheritance
Review topic 10.1 Meiosis II
Thomas morgan and non mendelian genetics
NoS: Looking for patterns, trends and discrepancies—Mendel used observations of the natural world to find and explain patterns and trends. Since then, scientists have looked for discrepancies and asked questions based on further observations to show exceptions to the rules. For example, Morgan discovered non-Mendelian ratios in his experiments with Drosophila. (3.1)
A1: Morgan’s discovery of non-Mendelian ratios in Drosophila.
Exercise 1: Watch the video and connect extend challenge.
gene linkage
Essential idea: Genes may be linked or unlinked and are inherited accordingly.
U1: Gene loci are said to be linked if on the same chromosome.
U2: Unlinked genes segregate independently as a result of meiosis.
Exercise 2: Outline how whether two genes are linked or unlinked affects how they are likely to be inherited together.
variation & polygenetic inheritance
A3: Polygenic traits such as human height may also be influenced by environmental factors.
U3: Variation can be discrete or continuous.
U4: The phenotypes of polygenic characteristics tend to show continuous variation.
Exercise 3: Complete the following questions:
What environmental factors may also influence human height?
What do we mean by discrete and continuous variation?
How do genes and the environment influence whether a trait shows discrete or continuous variation within a population?
Explain why phenotypes of polygenic characteristics show continuous variation?
predicting inheritance with more than one gene
U5: Chi-squared tests are used to determine whether the difference between an observed and expected frequency distribution is statistically significant.
S3: Use of a chi-squared test on data from dihybrid crosses.
A2: Completion and analysis of Punnett squares for dihybrid traits.
S1: Calculation of the predicted genotypic and phenotypic ratio of offspring of dihybrid crosses involving unlinked autosomal genes.
S2: Identification of recombinants in crosses involving two linked genes.
Guidance:
Alleles are usually shown side by side in dihybrid crosses, for example, TtBb. In representing crosses involving linkage, it is more common to show them as vertical pairs, for example:
This format will be used in examination papers, or students will be given sufficient information to allow them to deduce which alleles are linked.
Exercise 4: Complete the following exercises:
DP Topic 10.2 workbook (dragged).pdf